Principal Clinical Scientist

Principal Clinical Scientist (AI Training)

About the Role

What if your decades of clinical trial expertise could directly shape how AI reasons about medical evidence, regulatory data, and patient outcomes? We're looking for a Principal Clinical Scientist to bring senior-level rigor to the AI systems that are rapidly transforming biomedical research.

At Alignerr, we partner with the world's leading AI research teams to build and train cutting-edge models. In this role, your expertise in regulatory-grade trial design and clinical data interpretation won't just inform internal processes — it will influence how next-generation AI understands and evaluates real-world clinical evidence.

This is a fully remote, flexible contract role designed for senior clinical scientists who want meaningful, high-impact work on their own schedule.

• Organization: Alignerr
• Type: Hourly Contract
• Location: Remote
• Commitment: 10–40 hours/week

What You'll Do

• Design and review clinical trial protocols used to generate high-quality, regulator-ready datasets for AI training and evaluation
• Interpret and audit clinical trial results to ensure accuracy, consistency, and alignment with regulatory standards
• Evaluate AI-generated clinical analyses for scientific soundness and regulatory relevance
• Provide structured expert feedback that directly improves how AI models reason about clinical trial data, endpoints, and outcomes
• Help establish quality benchmarks for clinical content used across frontier AI systems

Who You Are

• Senior-level professional with hands-on experience designing clinical trial protocols for regulatory submission
• Deep expertise interpreting clinical data for agencies such as the FDA, EMA, or equivalent regulatory bodies
• Strong grounding in clinical research methodology, biostatistics, or translational science
• Meticulous, structured thinker who can communicate complex scientific judgments clearly and consistently
• Self-directed and comfortable working independently in an async, remote environment

Nice to Have

• Prior experience with data annotation, data quality assurance, or AI evaluation workflows
• Background in clinical pharmacology, outcomes research, or medical affairs
• Familiarity with AI tools or experience reviewing AI-generated scientific content

Why Join Us

• Work directly on frontier AI systems making a real impact on clinical and biomedical research
• Fully remote and flexible — work when and where it suits you
• Freelance autonomy with the structure of meaningful, expert-level work
• Collaborate with world-class AI research teams on problems that matter
• Potential for ongoing work and contract extension as new projects launch